Associate, DNA/RNA diagnostics (NGDx), BS/MS

Job Description
About Novartis Institute for Biomedical Research:
The Novartis Institutes for BioMedical Research is the global pharmaceutical research organization for Novartis. The NIBR research network is comprised of more than 6,000 scientists, physicians, and business professionals working together across 10 locations around the world to discover innovative medicines that treat diseases with high unmet medical need. Novartis employs more than 2,000 associates in Cambridge, making it the city's largest private employer and ideally situated in one of the leading life science communities in the world.

NIBR conducts research globally with sites in Emeryville, California; Cambridge, MA; East Hanover, NJ; Basel, Switzerland; Horsham, UK; and Shanghai, China.

About the Next Generation Sequencing Group
The ability to sequence each patient's genome in great detail, quickly and inexpensively, is changing the practice of medicine. At NIBR, we are dedicated to the development of therapies that improve clinical outcomes for patients. Next generation sequencing and other cutting-edge molecular characterization technologies will be important tools for discovering breakthrough therapeutics, and for delivering the right medicines to the right patients.

NIBR is launching a new Next Generation Diagnostics (NGDx) group at our global headquarters in Cambridge, MA. The NGDx team will leverage cutting-edge technologies such as next generation sequencing for characterizing human tissues, by individual lesions and by pathway signatures relevant to therapeutic response. The goal is to develop a robust and comprehensive molecular profile for each patient. To this end, the group will begin by developing capabilities to characterize therapeutically relevant genetic lesions and pathway signatures in human cancer.

Opportunities exist for genomics scientists, computational biologists, bioinformatics scientists, software and systems engineers, assay development scientists, histopathologists, sample technicians, and biochemists.

We are looking for highly qualified and motivated scientific associates to join the DNA and RNA analytical labs in the newly established Next Generation Diagnostics (NGDx) group within NIBR. At NIBR, we are dedicated to the development of therapies that improve clinical outcomes for patients. Our goal is to develop a robust and comprehensive molecular profile for each patient, and to deliver the right medicines to the right patients.

The successful candidate would be responsible for assistance in experiment design, handling of day to day experiments including DNA and / or RNA isolation, analysis, operating the Next Generation Sequencing platform, and providing basic data analysis and interpretation to his/ her supervisor. The candidate would also be expected to recognize problems, troubleshoot effectively, provide input on solutions, present experimental results at team meetings, and follow the established relevant laboratory HSE policies and procedures.

B.S. / M.S. in Molecular Biology, Biochemistry, Genetics or equivalent training plus 2-5 years industry or equivalent academia experience.

Proficiency in DNA and RNA isolation, DNA / RNA quantification technologies, and other associated molecular biology techniques is required.

Prior experience in conducting DNA and/ or RNA based assays, including next generation sequencing technologies is preferred

Experience with lab automation is a plus.

Candidates are required to have good organizational and interpersonal skills.

A working knowledge of data management, word processing, and graphical software is essential,

Experience working with large data sets is desirable, as well as excellent critical thinking skills and ability to work both independently and collaboratively are essential.


Novartis Corporation

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