| Job Description | NGM Biopharmaceuticals, Inc. is a biotech start-up dedicated to discovering the next
generation of medicines for the treatment of metabolic diseases. Our experienced
scientific team has joined forces with an impressive group of industry professionals,
Nobel Laureates, and other distinguished researchers to form a brand new company
where innovation and cutting edge science will provide the foundation for a robust drug
discovery engine.
We are currently looking for a creative and highly motivated Bioinformaticist to
contribute his/her superb technical skills and scientific expertise towards the discovery
of transformational new therapeutics. The successful candidate will take a lead role in
data mining, data visualization, statistical analysis, experimental design and database
development to support genomics-based discovery efforts at NGM. This individual will
be responsible for developing and managing a computational genomics platform and
the analysis of experimental data, enabling NGM’s research objectives with a focus on
the identification of therapeutic targets and biomarkers associated with the resolution of
diabetes following gastric bypass surgery. As a member of a multidisciplinary research
team, the bioinformaticist will:
• Develop, in collaboration with researchers, an integrated analysis platform for
genomics-based comparisons.
• Design and apply bioinformatics algorithms including machine learning, dynamic
programming or graphic algorithms and feature selection and pattern recognition
algorithms to find predictive patterns and enable biomarker discoveries.
• Develop and implement standardized protocols for data analysis and quality
control of genomics experiments, including background correction algorithms, data
normalization, principal component analysis, statistical inference methods, and
clustering algorithms.
• Provide statistical and computational tools for genomic analysis and measurement
of RNA expression.
• Manipulate publicly accessible, commercial, or proprietary genomic, proteomic, or
post-genomic databases.
• Design and apply computer systems and databases used to organize and analyze
large amounts of biological data.
• Oversee and provide technical guidance to enable the design, development and
maintenance of a biological database integrating data from diverse information
sources.
Qualifications. Applicants must have a Ph.D. degree in bioinformatics, computer
science, or life sciences-related field and 5+ years of relevant experience in
computational biology, including algorithm development, quality control data analysis
and hands-on data analysis. Knowledge of genomics and proteomics software /
platforms and sequence databases is a prerequisite for this position. Experience in
designing, developing and accessing software for genomics-based methods, including integration with RNA and protein databases, is desirable. Strong communication skills,
and the ability to work effectively as part of a research team, are essential |
| | Company | | NGM Biopharmaceuticals | Job Code | | State or Province | | California | | |
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