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Investigator II/III, Pharmacology
Job Description About Novartis Institute for Biomedical Research:
At Novartis Institutes for BioMedical Research (NIBR), the global research organization of Novartis, we are committed to discovering innovative medicines to cure disease and improve human health. We aim to hire the best trained scientists from academia, biotechnology and pharmaceuticals and we cultivate an environment for drug discovery science where innovation is rewarded. It is ultimately the talent of the individuals we recruit that determines our success and our state-of-the-art technologies and resources that enable individuals to realize this success.
About the Pharmacology Group
Oncology pharmacology develops and uses models of human cancer, contributing to antibody and small molecule drug discovery projects from target validation through early clinical development. This work includes elucidating PK/PD relationships, screening to select clinical development candidates, and studying mechanism of action in vivo, using disease and indication-relevant models.
The Oncology Pharmacology department at the Novartis Institutes of Biomedical Research is seeking a Research Investigator II/III with experience in developing and utilizing genetic mouse models of cancer.
The successful candidate will draw upon his/her knowledge of cancer biology and mouse models to develop and execute approaches to investigate tumor biology and identify new oncology drug candidates.
Responsibilities include leading a team of technical associates in developing, characterizing and maintaining mouse models, and identifying and implementing novel strategies to apply mouse models for the discovery and characterization of targeted cancer therapies.
This work will require the ability to transition between in biochemical/cellular assays, in vivo models, and ex vivo analyses of these models.
Additional opportunities in this role include collaboration with cancer biologists at Novartis and at academic centers to identify and validate novel oncology targets in genetic models of cancer.
Minimum requirements Qualifications include a Ph.D. in Molecular, Cell or Cancer Biology or a related field, with 3-12 years of relevant experience in genetic rodent models of cancer and a strong record of academic achievement. Experience in oncology drug discovery and characterization is desirable. The successful candidate will have strong written and verbal communication skills, and the ability to work as an influential member of collaborative and interdisciplinary teams in a dynamic and fast moving environment.
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