| Job Description | Warp Drive Bio is driving the reemergence of natural products in the era of genomics to create breakthrough
treatments that make an important difference in the lives of patients. Built upon the belief that nature is the worlds most powerful medicinal chemist, Warp Drive Bio is deploying a battery of state-of-the-art technologies to access powerful drugs that are now hidden within microbes.
The successful candidate will be responsible for the expression and purification of proteins from multiple expression
systems. The candidate will be expected to provide oversight on all protein production within the group, as well as
be able to participate in experimental design and independently conduct experiments in a fast-paced, start-up
environment.
Responsibilities may include, but are not limited to:
Molecular biology subcloning, PCR, sequencing and plasmid DNA preparation
Expression, optimization and scale-up of recombinant proteins and complexes from E.coli, baculovirus,
and mammalian expression systems (HEK293/CHO)
Protein purification (affinity, SEC and ion exchange)
Protein characterization (SDS-PAGE, western blot, HPLC, SEC-MALS, IEF, thermal shift assays, CD,
DLS)
Maintenance of inventory systems for all plasmids and proteins supporting discovery
Minimum Requirements:
Ph.D. in biochemistry or a related discipline with 5 plus years of research experience
Experience in molecular biology essential
Proven experience with multiple expression systems essential
Experience with protein purification and characterization essential
Experience outsourcing protein production would be a plus
Experience managing direct reports is an asset
Experience with biophysical characterization (Biacore, ProteOn) would be a plus.
Excellent attention to detail and strong documentation skills essential
Experience working in multi-disciplinary teams of scientists in a fast-paced environment to accomplish
project and company goals
Excellent verbal and written communications skills a must |
| | Company | | Warp Drive Bio, LLC | Job Code | | State or Province | | Massachusetts | | |
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