| Job Description | The Scientist is a key role within Intrexon’s Assay Development and Screening Operations (ADSO) unit, responsible for supporting the development, validation and implementation of high-throughput screening (HTS) assays along with designing and qualifying secondary characterization assays. The Scientist will help to realize the experimental requirements of Intrexon’s commercial divisions by utilizing a wide array of molecular and cell-based techniques ranging from low to high-throughput.
DUTIES AND RESPONSIBILITIES
• Develop and implement HTS screening assays that will have the capability and capacity to support multiple, ongoing orthogonal projects.
• Be a key member of the team that will support all of ADSO’s development and screening activities, encompassing a broad range of mammalian cell hosts, transcript-, protein- and enzyme-based approaches for expression and activity screening.
• Develop, validate and implement customized secondary assays for candidate characterization.
• Partner with ADSO key stakeholders, including the bio-informatics and Intrexon’s commercial divisions, to develop and implement customized HTS and secondary assays that will create high value commercial products.
• Work closely with external collaboration partners as applicable to support technology transfer and collaborative projects.
MANAGEMENT RESPONSIBILITIES
To be determined
EDUCATION AND EXPERIENCE
• Ph.D. in Biochemistry, Molecular Biology, Synthetic Biology, Biological Sciences or Chemistry or with 2+ years experience with a proven track record of accomplishments, preferably in the life sciences, pharmaceutical and chemical industries or BS/MS with 7+ years experience.
• Proficiency with high-throughput screening systems and automation (e.g., colony pickers, plate readers, FACS, automated liquid handling), preferably in developing and validating bio-analytical methods and systems.
• Experience in development and implementation of low- and high-throughput assay systems using standard and novel assay platforms (ELISA, qPCR, enzymatic activity assays, Luciferase assays, Western blot, cell-based assays, MSD, high-content imaging, microscopy, etc.)
• Significant experience in DNA manipulation and molecular biology for mammalian cells.
• Experienced in reviewing literature, creating research protocols and validating experimental protocols.
• Experience cultivating and analysis of mammalian cells required.
• Experienced mentoring junior scientists a plus.
• Experience in enzyme and binding kinetics a plus.
DESIRED KEY COMPETENCIES
• Strong personal leadership and self-direction.
• Well developed interpersonal skills and demonstrated ability to work with and coordinate demands from multiple customers, both internally and with partners.
• Demonstrated attention to detail and ability to effectively manage own projects and priorities.
• Strong oral and written communication skills and an ability to communicate complex concepts in a concise, simplified manner.
• Ability to handle a fast-paced, multi-tasking, global environment, and prioritize effectively.
• Strong quantitative and analytical skills.
• Demonstrates the highest ethical standards, trustworthiness and has a high degree of personal responsibility.
• Proficiency with MS Word, Excel, PowerPoint
- See more at: http://www.dna.com/Jobs/View.aspx?Id=244#sthash.6qYsgPCm.dpuf |
| | Company | | Intrexon Corporation | Job Code | | State or Province | | Maryland | | |
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