Scientist - Oncology

Job Description
If you are looking for an uncommon opportunity -- a chance to join an organization known for its scientific excellence in the research and development of pharmaceuticals -- it's time to consider Regeneron.

Founded on the principle that strong science would lead to important new medicines, Regeneron has become an integrated biopharmaceutical company that discovers, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions.

Regeneron currently markets ARCALYST (R) (rilonacept) Injection for Subcutaneous Use and EYLEA (TM) (aflibercept) Injection. Regeneron has therapeutic candidates in Phase 3 clinical trials for the prevention of gout flares, central retinal vein occlusion, diabetic macular edema, certain cancers, and rheumatoid arthritis. Additional therapeutic candidates are in earlier stage development programs in cholesterol reduction, allergic conditions, pain, and cancer.

As a key member of the Oncology team this scientist will be responsible for independently leading and/or contributing to studies in the area of tumor immunology. The scientist will lead a small team (1-2 RA's) and design and perform studies to validate and characterize the efficacy of novel therapeutic cancer antibodies and targets from pre-clinical discovery through clinical development stages. This scientist will effectively and frequently collaborate with colleagues in the oncology, immunology and antibody development groups as well as present scientific results to multidisciplinary teams and senior management.

Responsibilites include, but are not limited to:

-Ability to design, perform and interpret complex in vivo mouse xenograft experiments in both immunocompetent and immunocompromised mice

-Expertise in animal handling and development of novel tumor models (mice); dissection, orthotopic tumor model development

-Analysis and understanding of immune cells and molecules (rodent and human) as well as ex vivo analysis of immune cells by FACS, IHC and ELISA

-Expert in FACS methods, analysis and interpretation

-Cell/molecular biology: in vitro immune cell activation assays; basic cloning of stable cell lines; cell culture; analysis and purification of primary immune cells from murine tissues and human blood

-Ability to analyze and present data in professional 'publication ready' format

-Ability to manage multiple in vivo and in vitro experiments simultaneously

-Clear and professional verbal and written communication

-Ability to supervise and guide junior RA's


A PhD in a relevant scientific discipline (Tumor Immunology, Immunology, Oncology, Cell Biology) with >4 years post-doctoral experience (in academia or industry) is required.
In addtion, the ideal candidate will have:

-Knowledge of tumor immunology. Specifically, experience with in vivo mouse tumor models
and ex vivo measurement of immune endpoints will be an advantage, and is highly desired.

-Extensive experience with primary immune cells of human and/or rodent origin as well as a comprehensive knowledge of the basics of cellular immunology, as it applies to cancer.

- Excellent written and verbal communication skills.

- Some management experience is very desirable.

- Strong organizational skills including the ability to manage several projects simultaneously

- ability to effectively collaborate with colleagues in the oncology, immunology and antibody
development groups

- write reports and present scientific results to multidisciplinary teams and senior management.

The successful candidate is expected to work creatively, independently and collaboratively in a dynamic team environment. Strong analytical and critical thinking skills and attention to detail are critical for this position.

We offer a competitive compensation and benefits package including stock incentives, 401k with company match as well as the expected health and welfare benefits. Comprehensive relocation benefits are available, as required.

This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply to us today and find out what we mean when we say that, at Regeneron, we have an unwavering commitment to combining good science & good business.


Disclaimer: Regeneron is not accepting unsolicited assistance from search firms/employment agencies for this employment opportunity. Please, no phone calls or emails to any employee of Regeneron about this opening. All resumes submitted by search firms/employment agencies to any employee at Regeneron via-email, the Internet or in any form and/or method without a valid written search firm agreement in place for this position will be deemed the sole property of Regeneron. No fee will be paid in the event the candidate is hired by Regeneron as a result of the referral or through other means. Moving forward, Regeneron is using the agency management company, Candex -



Job Code

State or Province

New York

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