If you are looking for an uncommon opportunity -- a chance to join an organization known for its scientific excellence in the research and development of pharmaceuticals -- it's time to consider Regeneron.
Regeneron is a fully integrated biopharmaceutical company that discovers, invents, develops, manufactures, and commercializes medicines for the treatment of serious medical conditions. Regeneron markets three products in the United States, EYLEA (R) (aflibercept) Injection, ZALTRAP (R) (ziv-aflibercept) Injection for Intravenous Infusion, and ARCALYST (R) (rilonacept) Injection for Subcutaneous Use. Regeneron has filed a regulatory application with the U.S. Food and Drug Administration (FDA) for a second indication for EYLEA. Phase 3 studies are in progress with EYLEA in two additional indications and with product candidates sarilumab and REGN727. Regeneron has active research and development programs in many disease areas, including ophthalmology, inflammation, cancer, and hypercholesterolemia.
The Oncology/Angiogenesis group is looking for a Scientist. The successful candidate will be responsible for independently leading and/or contributing to studies in the area of tumor immunology including discovery and validation of therapeutic cancer targets using gene delivery and pharmacological approaches in preclinical mouse models.
The main duties of this position are to design, perform and analyze studies to screen and validate novel therapeutic cancer targets from pre-clinical discovery through clinical development stages. This scientist will effectively and frequently collaborate with colleagues in the oncology, immunology and antibody development groups as well as present scientific results to multidisciplinary teams. The successful candidate is expected to work creatively, independently and collaboratively in a dynamic team environment. Strong analytical and critical thinking skills and attention to detail are required for this position.
This position requires a PhD, with 3-5 years of post-doctoral training in academia or industry
TECHNICAL SKILLS REQUIRED:
- Comprehensive knowledge of the basics of cellular and molecular immunology, as it applies to cancer.
- Ability to design, perform and interpret complex in vivo experiments utilizing subcutaneous, orthotopic and transgenic tumor models in both immunocompetent and immunocompromised mice
- Isolation and characterization of primary immune cells from murine tissues and human blood
- Expertise in sterile cell culture techniques, and in vitro immune cell assays
- Expertise in FACS methods, analysis and interpretation
- Protein analysis and imaging including immunohistochemistry, immunofluorescence, Western and ELISA
- Experience with recombinant lentiviral vectors and antibody technology or development would be a plus
- Strong organizational and time-management skills including the ability to manage several projects simultaneously
- Demonstrated creativity
- Ability to effectively collaborate as part of cross-functional teams
- Clear and professional verbal and written communication
- Strong desire and aptitude for learning new skills and concepts
We offer a competitive compensation and benefits package including stock incentives, 401k with company match, as well as the expected health and welfare benefits. Comprehensive relocation benefits are available, as required.
This is an opportunity to join our select team that is already leading the way in the Pharmaceutical/Biotech industry. Apply to us today and find out what we mean when we say that, at Regeneron, we have an unwavering commitment to combining good science & good business.
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