Sr. Research Associate II/ Scientist I, Preclinical Development

Job Description
Description:

Geron is seeking a Sr. Research Associate II / Scientist I to join our ADME/PK group. The successful candidate should be experienced and proficient in developing and performing robust bioanalytical methods to support in vivo and in vitro drug metabolism and pharmacokinetics studies to contribute to Geron’s drug discovery and development efforts.

Responsibilities

Perform bioanalytical assays on non-clinical ADME/PK samples

Perform in vitro ADME assays, e.g. metabolic stability in microsomes, plasma, and hepatocytes, plasma protein binding, and metabolite identification

Managing CRO for clinical PK sample analysis

Hands-on experience with state-of-the-art bioanalytical equipment and methodology (HPLC, LC/MS/MS, and robotic liquid handler) is a must, as well as the ability to troubleshoot instrumentation related issues independently

Experience with tissue sample analysis, and different sample preparation techniques, e.g. SPE and LLE

Keep abreast of the scientific literature

Participate in department meetings and present data

Qualifications:

MS degree in biopharmaceutical sciences, biochemistry, biology, chemistry or related discipline with 5+ years relevant industrial experience in DMPK, or Ph.D. degree with 1-2 years of industry experience

The candidate should be self-motivated, detail oriented, fast learner, proactive in problem solving, meticulous in record keeping and documentation, and able to manage timelines and priorities

The candidate should be able to work both independently and as part of a team, and have a desire to learn new methods and to work on new assignments

Experience in GLP regulations and environment is preferred

Company

Geron

Job Code

State or Province

California

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