| Job Description | Founded in 1849, Pfizer is the world's premier biopharmaceutical company taking new approaches to better health. We discover, develop, manufacture and deliver quality, safe and effective prescription medicines to treat and help prevent disease for both people and animals. We also partner with healthcare providers, governments and local communities around the world to expand access to our medicines and to provide better quality health care and health system support. At Pfizer, colleagues in more than 90 countries work every day to help people stay happier and healthier longer and to reduce the human and economic burden of disease worldwide.
Role Description
The leader of the Therapeutic Area unit will be responsible for delivering successful programs from early exploratory biology through positive Proof-of-Concept (POC) programs. This leader will be a driver of innovation and scientific excellence, advancing the best novel therapeutic hypotheses, targets and molecules. This scientific leader will be expected to create a department recognized as a pioneer in its field by driving and responding to rapidly breaking science and evolving global healthcare demands. Programs from this department will help position the Pfizer neuroscience portfolio as one of the most valuable and innovative pipelines across the industry.
Lead a Therapeutic area department of the Neuroscience Research Unit, responsible for identifying novel targets or pathways to treat Invest to Win Neuroscience diseases areas in psychiatric disease, cognition, and neurodevelopment.
Deliver highly competitive, positive POCs that fulfill product concepts defined by TA strategy.
Identify and unite emerging science with unmet medical needs. Drive and prosecute a balanced and innovative therapeutic area portfolio of small molecule and biologic based targets, critically prioritized based on rigorous and innovative science. These programs will be derived from discoveries internal to PharmTx, from collaborations with external biomedical research groups, from partnerships with BioTx, or from the licensing of external candidates from biotech.
Advance programs by the most effective means to test convincingly in humans.
Build a pipeline of clinical candidates with strong and clear rationale for differentiation from standard of care and achieve a return on investment in the Research Unit commensurate with Pfizers financial objectives.
Nurture a culture which engages Pfizer colleagues internal and external to the RU to enthusiastically and optimistically strive for the discovery of new Neuroscience medicines. Actively seek, embrace, and apply the best biomedical research to discovering new drugs and win the race with competitors to deliver first in class medicines.
Organizational Relationships:
Reports to the Chief Scientific Officer for Neuroscience and is a member of the Neuroscience executive leadership team
Leads a therapeutic area department comprised of approx 25-30 FTEs, supervising scientific leaders from a range of biology disciplines such as molecular and cellular neurobiology, neuropharmacology, biochemistry, neurochemistry, electrophysiology, behavioral and translational sciences.
Liaises with resource holders such as other Research Areas, Development lines, BioTx, to maximize the value and delivery of neuroscience portfolio.
Liaises with members of the NS Therapeutic Area Scientific Advisory Panel (TASAP).
Resources Managed:
Manages budget for the therapeutic area, including internal and external headcount, licensing recommendations and investments and external collaborations with biomedical researchers.
Responsibilities
Strategy:
Set priorities aligned with the strategic direction from the RU; single point of accountability for the delivery of the therapeutic area portfolio from Target ID to candidate.
Partner with Clinical Head and Clinical Team to deliver differentiated and innovative medicines through to positive proof of concept (POC).
In conjunction with the Neuroscience CSO ,define strategies to identify breakthrough medicines for Neuroscience Diseases. Contribute to the development of the RUs idea-to-POC strategy by liaising with the Neuroscience Scientific and Clinical Executive team and appropriate BU leadership.
Collaborate with key internal and external biomedical scientists to drive improved understanding of disease pathophysiology to deliver a highly competitive and innovative drug discovery portfolio.
Set objectives for the therapeutic area to generate an appropriate return on investment.
Influence the global external environment through thought leadership, external visibility and active engagement with key opinion leaders
Foster a collaborative and productive environment between Pfizer NS RU and academic biomedical researchers.
Portfolio:
Deliver a sustainable, highly competitive pipeline from target-to-POC.
Ensure scientific strategy for each drug discovery project is rigorous, aligned and effective.
Interface with senior PharmTx and BioTX leaders to ensure target-to-POC portfolio balances risk with opportunity, and exploits the full repertoire of therapeutic modalities.
Management:
Ensure all activities executed comply with legal and regulatory requirements and with Pfizer corporate policies.
Build an intelligence capability and external network of biomedical research collaborations and advisors to find the most attractive therapeutic mechanisms.
Ensure projects are adequately resourced and prioritized to deliver on objectives.
Eliminate barriers and silos that inhibit collaboration across departments and line functions and foster a culture of open collaboration, communication and transparency.
Communication:
Clearly communicate and articulate the vision and strategy to stakeholders and regularly report on portfolio progress.
Inspire, model, and reinforce colleague expectations of urgently creating value at an appropriate return on investment, of applying innovative, rigorous science to discovering new medicines, of individual & collective accountability for value creation, of continuously improving organizational effectiveness.
Build a cohort of colleagues with the quality of scientific leadership and external recognition to generate competitive advantage in attracting the best talent and collaborators.
Engender a high level of engagement across both direct and indirect lines.
Attract and grow highly effective scientists and drug discoverers and nurture a culture which translates breaking biological science into new medicines more effectively than the competition.
Effectively, rigorously and accurately review and develop talent. Proactively address development needs and make difficult decisions when appropriate.
Qualifications
Training & Education Preferred:
M.D., Ph.D., or M.D./Ph.D.
Deep working knowledge of medical practice, diseases and biology relevant to Neuroscience
Knowledge of competitive landscape for therapeutic area.
Prior Experience Preferred:
9-15 years experience in research
Recognized deep biological expertise and innovative record of research in therapeutic area.
Established record of delivering high quality drug candidates
Established national and international scientific reputation
Demonstrated track record of high impact publications
Record of team leadership including change management experience
TECHNICAL COMPETENCIES:
Scientific leader in his or her field as demonstrated by external reputation (e.g. publications, editorials appointments and podium presentations at top level scientific meetings)
A compelling and inspiring leader with a sharp scientific mind, who combines broad knowledge and understanding of biological systems with being a world-class leader in his/her field of biomedical research.
Decision making and problem solving profile which enables marrying emerging science with unmet medical need to identify potential breakthrough medicines, uses this experience to build a sustainable pipeline of drug candidates. Adept at separating important from unimportant information.
Combines knowledge from multiple sources to generate novel and high impact ideas. Gets to the core of the problem, asks insightful and probing questions and gets to the next step effectively.
Strategically and rigorously assess projects in light of overall pipeline strategy and quickly and decisively advances or terminates projects.
Disaggregates complex problems to facilitate problem solving.
Business mindset; teases out and understands risks inherent in drug discovery (small molecule and biotherapeutic), and makes decisions appropriate to opportunity and investment required.
Thinks laterally, connecting seemingly unrelated data, information, perspectives etc, at people, scientific and business levels.
Viewed internally and externally as a top scientific leader with respect to drug discovery and in the field of biology underpinning the TA.
LEADERSHIP MANAGEMENT OF SELF:
Is able to create an aspirational vision and express it in a compelling fashion to all levels of the organization.
A natural collaborator who forges strong relationships and alliances at all levels, internally & externally, attracting ideas, catalyzing new thinking and galvanizing action.
Instinctively decisive, with an entrepreneurial mindset driven by a passion for applying science to create value at an attractive ROI for Pfizer. Able to balance risk with opportunity to deliver.
Effective at the strategic and detail level, and moves between the two levels effortlessly.
Situational leader; resilient, assured and decisive under pressure or faced with ambiguity, willing to step into a leadership role in any situation which demands it.
Manages her/himself through change rapidly and in a way which assures those around them
Sophisticated interpersonal skills, exhibits empathy with others frame of reference, perceives impact of actions & words on those around her/him, draws ideas out from others regardless of origin and builds upon them, provides open & frank feedback (both positive & negative) in a constructive fashion, tailors coaching style to recipient.
Team player, adaptable to many different roles within a team.
Networks and builds effective working relationships both inside and outside her/his area of responsibility.
Navigates effectively through complex organizational relationships (internal & external) to make things happen.
LEADERSHIP MANAGEMENT OF OTHERS:
Demonstrated ability to energize and motivate talent from top to bottom and bottom to top.
Accurately assesses talent and puts colleagues in roles commensurate with their skills, motivation and abilities. Builds high potential employees and makes tough decisions regarding unproductive employees. Champions talent and proactively supports the development of colleagues.
Paints a vivid picture of the strategy which is relevant and inspiring to all
Leads change effectively through knowledge and experience of driving change previously.
Engenders trust, respect and confidence as a leader.
Delegates to and holds individuals accountable for delivering on objectives and for modeling & reinforcing the aims and culture of the unit. Manages performance of reports effectively.
Judges competence and motivation of others effectively.
Equal Employment Opportunity
Pfizer is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status. Pfizer also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must have authorization to work for Pfizer in the U.S. In certain circumstances it may be advantageous to Pfizer to support the application(s) for temporary visa classification and/or sponsor applications for permanent residence so that a foreign national colleague can accept or remain in a work assignment in the U. S. For certain classes of temporary visas, the resulting work authorization may be specific to Pfizer and the specific job and/or work site. Pfizer may at its business discretion decide to or refrain from obtaining, maintaining and/or extending the temporary visa status and/or sponsoring a colleague for permanent residency and /or employment eligibility, considering factors such as availability of qualified U.S. workers and the colleague's long-term prospects for securing lawful permanent residence, among other reasons. Employment applicants requiring immigration sponsorship must disclose, when initial application for employment is made, whether or not they are legally authorized to work for Pfizer in the U.S. and, if so, whether that authorization permits them to work in the job they seek. In no case should Pfizer's support of a colleague's temporary visa application or sponsorship of a colleague for permanent residence be construed to guarantee success of that application or amend or otherwise invalidate the ""at-will"" employment relationship between the colleague and Pfizer. ύ |
| | Company | | Pfizer | Job Code | | State or Province | | Massachusetts | | |
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