Vice President

Job Description
Translational Medicine

Kolltan Pharmaceuticals, Inc. seeks a full-time Vice President, Translational Medicine to be part of the Kolltan senior management team and to play a key role to advance the pipeline and the Company’s business plan. The individual will report to the CEO. The desired starting date for this position is in the third quarter of 2012.

The responsibilities for this position include: (i) providing scientific leadership in defining development projects and portfolio for development opportunities and go/no-go decision-making through internal development and external collaborations; (ii) overseeing and providing input into design and execution of preclinical development including management of nonclinical and safety testing, management of CROs, collaborators and in-house efforts to assess preclinical pharmacology, disease linkage and PK/PD, (iii) biomarker discovery, histologic testing and PHC development to support Phase 1 clinical pharmacology, human PK/PD and patient selection in clinical trials, and (iv) generating, managing and safeguarding intellectual property. The responsibilities also include working closely with external collaborators, Product Development, Regulatory, Medical, and Research functions to advance and evaluate products into the clinic. This individual will drive programs ensuring budget, timeline, resources and goals are met.
In addition, the VP of Translational Medicine will work closely and collaboratively with the VP of Research and research project team leaders to provide support for efficacy, PK/PD and safety assessment, guidance on clinical indications, and other aspects of drug development strategy to help inform preclinical evaluation and drug candidate selection.


The candidate should hold a Ph.D., M.D., D.V.M, or Pharm.D. and have at least ten years of R&D experience in oncology or inflammatory diseases in the pharmaceutical or biotechnology industry supporting translational medicine strategies, IND filings and innovative Phase 1 trials. The individual should have led or was a key stakeholder in product development teams that advanced products into clinical evaluation. An excellent understanding of competitive landscape, working knowledge of current clinical trial design, biomarker studies and endpoints are essential. Problem solving and strategic thinking with attention to details are required. Solid experience should have been demonstrated recruiting and leading teams of scientists and managers. Must be able to initiate, manage, and lead collaborations with CROs, academia and industry partners. Applicants need to have a strong record of scientific publication, strong presentation skills, and record of patent filings. Leadership and expertise generating science-driven development approaches that can transition into clinical development and enable drug candidate decision-making and advancement are required.


Kolltan Pharmaceuticals

Job Code

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