CytomX Therapeutics is a venture-backed biotechnology company developing Probodies, or proteolytically-activated antibodies. Probodies, by their ability to site-direct the activity of antibodies, offer an improved therapeutic index for validated targets as well as enabling the drugging of entire new classes of antibody targets with broad tissue expression that thus far have been considered inaccessible.
Reporting to the Chief Scientific Officer, the successful candidate will lead internal efforts towards the integrated application of protease biology, cell biology and pharmacology capabilities to the identification of novel targets for Probody therapeutic development and evaluation of Probody candidates to enable their advancement towards the clinic. This senior position offers broad scope for leadership within CytomX and will require considerable interaction with the external scientific and clinical research communities, and with the CytomX Scientific Advisory Board.
The ideal candidate for this key position will hold a PhD degree, with at least 10 years of relevant experience in the biopharmaceutical industry, and will have a record of success in leading projects in biologics target selection and biomarker identification, in a variety of therapeutic areas, including oncology and immunology. A strong background in in vivo experimental design and interpretation, candidate molecule selection and establishment of key success criteria is essential. The ability to bring critical thinking to bear on complex biological problems is also essential. The incumbent should have a high level of organizational and management skills, as well as a proven track record of experience in leading the transition of research projects through late pre-clinical development. The successful candidate will be a highly motivated and goal driven self-starter who has excellent communication skills and a demonstrated ability to deliver in a fast paced environment.
|CytomX Therapeutics, Inc.|
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